Advocacy for Global Health Partnerships (AGHP) was established in 2017 as a coalition of global health stakeholders committed to promoting ethical standards in short-term global health engagements. Initially formed during a side event at the Consortium of Universities for Global Health (CUGH) conference, AGHP gradually transitioned from a loose network of concerned individuals into a more structured entity focused on advancing ethical practices in global health.

AGHP's first major initiative was the "Brocher Declaration," a set of guiding ethical principles for short-term global health engagements, which it intended to launch at a 2020 conference at the Brocher Foundation in Geneva, Switzerland. Although the event was postponed due to the COVID-19 pandemic, AGHP sustained its momentum through virtual global consultations, refining the Declaration, which was officially released later in 2020. Now endorsed by over 50 global organizations, the Declaration emphasizes key principles such as mutual partnership, local empowerment, sustainability, and accountability.

In 2022, AGHP convened at the Brocher Foundation, bringing together global stakeholders to reassess its focus on short-term health engagements. During that meeting, AGHP expanded its mission to encompass broader global health partnerships beyond the short-term engagements outlined in the Brocher Declaration. As part of its commitment to challenging conventional models, AGHP established its secretariat at the Uganda National Academy of Sciences (UNAS) in Kampala. Since then, AGHP has continued to foster dialogue intended to strengthen global health partnerships.

In 2023, AGHP organized a side event at the headquarters of GAVI and The Global Fund during the World Health Assembly. The event, which drew a standing-room-only crowd of key global health actors, underscored the ongoing need to address inequities in global health partnerships. As a result, AGHP commissioned a study through UNAS to examine equity in global health collaborations, which was released in 2024. Also in 2024, AGHP launched a community of practice for organizations that have signed the Brocher Declaration, providing a space for shared learning and collaboration among those involved in global health partnerships.